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2. Rollison D.E., Howlader N., Smith M.T., et al. Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001-2004, using data from the NAACCR and SEER programs / Rollison D.E., Howlader N., Smith M.T., et al. // Blood. - 2008. - Т.112. №1. - С.45-52.
3. Tefferi F. the history of myeloproliferative disorders: before and after Dameshek. Leykemia 2008; 22:3-13.
4. Jones, A.V. Cross et al. Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders / A.V.Jones, S. Kreil, K. Zoi et al. // Blood. - 2005. - Vol.106 №6. - P.2162-2168.
5. Campbell P.J., Scott L.M., Buck G., et al. Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on
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mutation status: a prospective study / Campbell P.J., Scott L.M., Buck G., et al. // The Lancet. - 2005. - Т.366. №9501. - С.1945-1953.
6. Tefferi A. Classification, Diagnosis and Management of Myeloproliferative Disorders in the
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Era / Tefferi A. // ASH Education Program Book. - 2006. - Т.2006. №1. - С.240-245.
7. Vannucchi A.M., Pieri L. and Guglielmelli P.
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8. Pardanani A, Lasho TL, Finke C, Hanson CA, Tefferi A. Prevalence and clinicopathologic correlates of JAK2 exon 12 mutations in JAK2V617F-negative polycythemia vera. Leukemia 2007;21:1960-1963.
9. Vannucchi AM, Antonioli E, Guglielmelli P, Pardanani A, Tefferi A. Clinical correlates of JAK2V617F presence or allele burden in myeloproliferative neoplasms: A critical reappraisal. Leukemia 2008;22:1299-1307.
10. Tefferi A, Thiele J, Orazi A, et al. Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: Recommendations from an ad hoc international expert panel. Blood 2007;110:1092-1097
11. Tefferi A. Pathogenesis of myelofibrosis with myeloid metaplasia. J Clin Oncol. 2005 Nov 20;23(33):8520-30.
12. Campbell PJ, Scott LM, Baxter EJ, Bench AJ, Green AR, Erber WN. Methods for the detection of the JAK2 V617F mutation in human myeloproliferative disorders. Methods Mol Med. 2006;125:253-64.
13. Pardanani A, Lasho TL, Finke CM, Tefferi A. Infrequent occurrence of MPL exon 10 mutations in polycythemia vera and post-polycythemia vera myelofibrosis. Am J Hematol 2011;86:701-702.
14. Ohashi H, Arita K, Fukami S, et al. Two rare MPL gene mutations in patients with essential thrombocythemia. Int J Hematol 2009;90:431-432.
15. Beer PA, Campbell PJ, Scott LM, et al. MPL mutations in myeloproliferative disorders: Analysis of the PT-1 cohort. Blood 2008;112:141-149.
16. Ding J, Komatsu H, Wakita A, et al. Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin. Blood 2004;103:4198-4200.
17. Liu K, Martini M, Rocca B, et al. Evidence for a founder effect of the MPLS505N mutation in eight Italian pedigrees with hereditary thrombocythemia. Haematologica 2009;94:1368-1374.
18. Pardanani A, Guglielmelli P, Lasho TL, et al. Primary myelofibrosis with or without mutant MPL: Comparison of survival and clinical features involving 603 patients. Leukemia 2011;25:1834-1839.
19. Vannucchi AM, Antonioli E, Guglielmelli P, et al. Characteristics and clinical correlates of MPL 515W>L/K mutation in essential thrombocythemia. Blood 2008;112:844-847.
20. Guglielmelli P, Pancrazzi A, Bergamaschi G, et al. Anaemia characterizes patients with myelofibrosis harbouring Mpl mutation. Br J Haematol 2007; 137:244-247.
21. Carobbio A, Thiele J, Passamonti F, et al. Risk factors for arterial and venous thrombosis in WHO-defined essential thrombocythemia: An international study of 891 patients. Blood 2011;117:5857-5859.
22. Passamonti F, Rumi E, Pietra D, et al. A prospective study of 338 patients with polycythemia vera: The impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications. Leukemia 2010;24:1574-1579.
23. Passamonti F, Elena C, Schnittger S, et al. Molecular and clinical features of the myeloproliferative neoplasm associated with JAK2 exon 12 mutations. Blood 2011;117:2813-2816.
24. Vannucchi AM, Antonioli E, Guglielmelli P, Rambaldi A, Barosi G, Marchioli R, Marfisi RM, Finazzi G, Guerini V, Fabris F, Randi ML, De Stefano V, Caberlon S,Tafuri A, Ruggeri M, Specchia G, Liso V, Rossi E, Pogliani E, Gugliotta L, Bosi A, Barbui T Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera or essential thrombocythemia. Blood. 2007 Aug 1;110(3):840-6. Epub 2007 Mar 22.
25. Klampfl T., Gisslinger H., Harutyunyan A.S. et.al. Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms.// N Engl J Med. 2013 Dec 10. [Epub ahead of print].
26. Nangalia J, Massie CE, Baxter EJ et.al. Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2.// N Engl J Med. 2013 Dec 10. [Epub ahead of print].
27. Tefferi A, Lasho TL, Abdel-Wahab O, et al. IDH1 and IDH2 mutation studies in1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis. Leukemia 2010;24:1302-1309.
28. Tefferi A, Pardanani A, Lim KH, et al. TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis, Leukemia 2009;23:905-911.
29. Brecqueville M, Rey J, Bertucci F, et al. Mutation analysis of ASXL1, CBL, DNMT3A, IDH1, IDH2, JAK2, MPL, NF1, SF3B1, SUZ12, and TET2 in myeloproliferative neoplasms. Genes Chromosomes Cancer 2012;51:743-755.
30. Stegelmann F, Bullinger L, Schlenk RF, et al. DNMT3A mutations in myeloproliferative neoplasms. Leukemia 2011;25:1217-1219
31. Guglielmelli P, Biamonte F, Score J, Hidalgo-Curtis C, Cervantes F, Maffioli M, Fanelli T, Ernst T, Winkelman N, Jones AV, Zoi K, Reiter A, Duncombe A, Villani L, Bosi A, Barosi G, Cross NC, Vannucchi AM EZH2 mutational status predicts poor survival in myelofibrosis. Blood. 2011 Nov 10;118(19):5227-34. doi: 10.1182/blood-2011-06-363424. Epub 2011 Sep 14.
32. Brecqueville M, Rey J, Bertucci F, et al. Mutation analysis of ASXL1, CBL, DNMT3A, IDH1, IDH2, JAK2, MPL, NF1, SF3B1, SUZ12, and TET2 in myeloproliferative neoplasms. Genes Chromosomes Cancer 2012;51:743-755.
33. Varricchio L., Mancini A. and Anna Rita Migliaccio. Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis.// Expert Rev Hematol. Author manuscript; 2009; June 1. 2(3). PP.315-334].
34. Tefferi A., Pathogenesis of Myelofibrosis With Myeloid Metaplasia. Journal of Clinical Oncology, 2005. 23(33): p. 8520-8530.
35. Cho S.Y., M. Xu, J. Roboz, M. Lu, J. Mascarenhas, and R. Hoffman, The Effect of CXCL12 Processing on CD34+ Cell Migration in Myeloproliferative Neoplasms. Cancer Research, 2010. 70(8): p. 3402-3410.
36. Massa M., V. Rosti, I. Ramajoli, R. Campanelli, A. Pecci, G. Viarengo, V. Meli, M. Marchetti, R. Hoffman, and G. Barosi, Circulating CD34+, CD133+, and Vascular Endothelial Growth Factor Receptor 2-Positive Endothelial Progenitor Cells in Myelofibrosis With Myeloid Metaplasia. Journal of Clinical Oncology, 2005. 23(24): p. 56885695.
37. Schmitt A., H. Jouault, J. Guichard, F. Wendling, A. Drouin, and E.M. Cramer, Pathologic interaction between megakaryocytes and polymorphonuclear leukocytes in myelofibrosis. Blood, 2000. 96(4): p. 1342-1347.
38. Cervantes F., A. Alvarez-Larran, C. Talarn, M. Gomez, and E. Montserrat, Myelofibrosis with myeloid metaplasia following essential thrombocythaemia: actuarial probability, presenting characteristics and evolution in a series of 195 patients. British Journal of Haematology, 2002. 118(3): p. 786-790.
39. Passamonti F., E. Rumi, L. Arcaini, E. Boveri, C. Elena, D. Pietra, S. Boggi, C. Astori, P. Bernasconi, M. Varettoni, E. Brusamolino, C. Pascutto, and M. Lazzarino, Prognostic factors for thrombosis, myelofibrosis, and leukemia in essential thrombocythemia: a study of 605 patients. Haematologica, 2008. 93(11): p. 1645-1651.
40. Wolanskyj A.P., S.M. Schwager, R.F. McClure, D.R. Larson, and A. Tefferi, Essential Thrombocythemia Beyond the First Decade: Life Expectancy, Long-term Complication Rates, and Prognostic Factors. Mayo Clinic Proceedings, 2006. 81(2): p. 159-166.
41. Kiladjian J.-J., J.-D. Rain, J.-F. Bernard, J. Briere, C. Chomienne, and P. Fenaux, Long-Term Incidence of Hematological Evolution in Three French Prospective Studies of Hydroxyurea and Pipobroman in Polycythemia Vera and Essential Thrombocythemia. Semin Thromb Hemost, 2006. 32(04): p. 417-421.
42. Passamonti F., E. Rumi, L. Arcaini, E. Boveri, C. Elena, D. Pietra, S. Boggi, C. Astori, P. Bernasconi, M. Varettoni, E. Brusamolino, C. Pascutto, and M. Lazzarino, Prognostic factors for thrombosis, myelofibrosis, and leukemia in essential thrombocythemia: a study of 605 patients. Haematologica, 2008. 93(11): p. 1645-1651.
43. Tefferi, A. Circulating Interleukin (IL)-8, IL-2R, IL-12, and IL-15 Levels Are Independently Prognostic in Primary Myelofibrosis: A Comprehensive Cytokine Profiling Study / A.Tefferi, R.Vaidya, D.Caramazza et al. // Journal of Clinical Oncology. - 2011. - Vol.29 №10. - P.1356-1363.
44. Tefferi A, Thiele J, Orazi A, et al. Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: Recommendations from an ad hoc international expert panel. Blood 2007;110:1092-1097.
45. Mossuz P, Girodon F, Donnard M, et al. Diagnostic value of serum erythropoietin level in patients with absolute erythrocytosis. Haematologica 2004;89: 1194-1198.
46. Crisa E, Venturino E, Passera R, et al. A retrospective study on 226 polycythemia vera patients: impact of median hematocrit value on clinical outcomes and survival improvement with anti-thrombotic prophylaxis and nonalkylating drugs. Ann Hematol 2010;89:691-699.
47. Diehn F, Tefferi A. Pruritus in polycythaemia vera: Prevalence, laboratory correlates and management. Br J Haematol 2001;115:619-621.
48. Finazzi G, Barbui T. Evidence and expertise in the management of polycythemia vera and essential thrombocythemia. Leukemia 2008;22:1494-1502.
49. Barbui T, Finazzi G, Carobbio A, et al. Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis). Blood 2012;120:5128-5133; quiz 5252.
50. Tefferi A. et.al. Polycythemia vera and essential thrombocythemia: 2012 update on diagnosis, risk stratification, and management.// American Journal of Hematology. 2012 (87). 285-293.
51. Barbui T, Barosi G., Birgegard G. et.al. Philadelphia-Negative Classical Myeloproliferative Neoplasms: Critical Concepts and Management Recommendations From European LeukemiaNet.//JCO. 2011. 29(6). 761-770.
52. Michiels JJ, Berneman Z, Schroyens W, et al. The paradox of platelet activation and impaired function: platelet-von Willebrand factor interactions, and the etiology of thrombotic and hemorrhagic manifestations in essential thrombocythemia and polycythemia vera. Semin Thromb Hemost 2006;32:589604.].
53. Budde U, Schaefer G, Mueller N, et al. Acquired von Willebrand’s disease in the myeloproliferative syndrome. Blood 1984;64:981-985.
54. Pardanani A, Vannucchi AM, Passamonti F, Cervantes F, Barbui T, Tefferi A. JAK inhibitor therapy for myelofibrosis: Critical assessment of value and limitations. Leukemia 2011;25:218-225
55. Pardanani A, Gotlib JR, Jamieson C, et al. Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis. J Clin Oncol 2011;29:789-796.
56. Barbui T.et al. Philadelphia-Negative Classical Myeloproliferative Neoplasms: Critical Concepts and Management Recommendations From European LeukemiaNet. JCO, 2011. 29(6): p. 761-770.
57. Verstovsek S. et al. Long-Term Efficacy and Safety Results From a Phase II Study of Ruxolitinib in Patients with Polycythemia Vera. ASH Annual Meeting Abstracts, 2012. 120(21): p. 804
58. Marchioli R, Finazzi G, Specchia G, et al. Cardiovascular events and intensity of treatment in polycythemia vera. New Engl J Med 2013;368:22-33.
59. Landolfi R, Marchioli R, Kutti J, et al. Efficacy and safety of low-dose aspirin in polycythemia vera. N Engl J Med 2004;350:114-124.
60. Pascale S, Petrucci G, Dragani A, et al. Aspirin-insensitive thromboxane biosynthesis in essential thrombocythemia is explained by accelerated renewal of the drug target. Blood 2012;119:3595-3603
61. Finazzi G. A prospective analysis of thrombotic events in the European collaboration study on low-dose aspirin in polycythemia (ECLAP). Pathol Biol (Paris) 2004;52:285-288
62. Ayalew Tefferi Polycythemia vera and essential thrombocythemia: 2013 update on diagnosis, risk-stratification, and management American Journal of Hematology Volume 88, Issue 6, pages 507-516, June 2013
63. Passamonti F How I treat polycythemia vera. Blood. 2012 Jul 12;120(2):275-84. doi: 10.1182/blood-2012-02-366054. Epub 2012 May 18
64. Fruchtman SM, Mack K, Kaplan ME, Peterson P, Berk PD, Wasserman LR From efficacy to safety: a Polycythemia Vera Study group report on hydroxyurea in patients with polycythemia vera. Semin Hematol. 1997 Jan;34(1):17-23.
65. Barosi G. et al A unified definition of clinical resistance and intolerance to hydroxycarbamide in polycythaemia vera and primary myelofibrosis: results of a European LeukemiaNet (ELN) consensus process. British Journal of Haematology, 2010.
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66. Quintas-Cardama A, Kantarjian H, Manshouri T, et al. Pegylated interferon alfa-2a yields high rates of hematologic and molecular response in patients with advanced essential thrombocythemia and polycythemia vera. J Clin Oncol 2009;
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67. Kiladjian JJ, Chomienne C, Fenaux P. Interferon-alpha therapy in bcr-abl-negative myeloproliferative neoplasms. Leukemia. 2008 Nov;22(11):1990-8. doi: 10.1038/leu.2008.280. Epub 2008 Oct 9
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69. Barosi G, Mesa R, Finazzi G, et al. Revised response criteria for polycythemia vera and essential thrombocythemia: an ELN and IWG-MRT consensus project. Blood. 2013 Jun 6;121(23):4778-81. doi: 10.1182/blood-2013-01-478891. Epub 2013 Apr 16.
70. Mesa R.A., M.N. Silverstein, S.J. Jacobsen, P.C. Wollan, and A. Tefferi, Population-based incidence and survival figures in essential thrombocythemia and agnogenic myeloid metaplasia: An Olmsted county study, 1976-1995. American Journal of Hematology, 1999. 61(1): p. 10-15.
71. Tefferi A., L.A. Solberg, and M.N. Silverstein, A clinical update in polycythemia vera and essential thrombocythemia. The American journal of medicine, 2000. 109(2): p. 141-149.
72. Alvarez-Larran A., F. Cervantes, B. Bellosillo, et al. Essential Thrombocythemia in Young Individuals: Frequency and Risk Factors for Vascular Events and Evolution to Myelofibrosis in 126 Patients. ASH Annual Meeting Abstracts, 2006. 108(11): p. 3598-.
73. Palandri F., N. Polverelli, E. Ottaviani, F. Castagnetti, M. Baccarani, and N. Vianelli, Long-term follow-up of essential thrombocythemia in young adults: treatment strategies, major thrombotic complications and pregnancy outcomes. A study of 76 patients. Haematologica, 2010. 95(6): p. 1038-1040.
74. Mesa R.A., M.N. Silverstein, S.J. Jacobsen, P.C. Wollan, and A. Tefferi, Population-based incidence and survival figures in essential thrombocythemia and agnogenic myeloid metaplasia: An Olmsted county study, 1976-1995. American Journal of Hematology, 1999. 61(1): p. 10-15.
75. Shuvaev V.A. Essential thrombocythemia - population analysis, a single center 10-years’experience. / V.A.Shuvaev, A.S.Abdulkadyrova, I.S.Martynkevich et al. ELN Frontiers Meeting «New Frontiers of Myeloid Neoplasias» 11-13 October, 2013, Prague, Czech Republic// ELN Information letter October 2013. - p.21
76. Thiele J, Kvasnicka HM, Vardiman JW, et al. Bone marrow fibrosis and diagnosis of essential thrombocythemia. J Clin Oncol 2009;27:e220-221; author reply e222-223.
77. Schmitt-Graeff AH, Teo SS, Olschewski M, et al. JAK2V617F mutation status identifies subtypes of refractory anemia with ringed sideroblasts associated with marked thrombocytosis. Haematologica 2008;93:34-40.
78. Kvasnicka HM, Thiele J. Prodromal myeloproliferative neoplasms: The 2008 WHO classification. Am J Hematol 2010;85:62-69.
79. Mesa R.A., M.N. Silverstein, S.J. Jacobsen, P.C. Wollan, and A. Tefferi, Population-based incidence and survival figures in essential thrombocythemia and agnogenic myeloid metaplasia: An Olmsted county study, 1976-1995. American Journal of Hematology, 1999. 61(1): p. 10-15.
80. Alvarez-Larran A, Cervantes F, Pereira A, et al. Observation versus antiplatelet therapy as primary prophylaxis for thrombosis in low-risk essential thrombocythemia. Blood 2010;116:1205-1210; quiz 1387.
81. Michiels JJ, Berneman Z, Schroyens W, et al. Platelet-mediated erythromelalgic, cerebral, ocular and coronary microvascular ischemic and thrombotic manifestations in patients with essential thrombocythemia and polycythemia vera: A distinct aspirin-responsive and coumadin-resistant arterial thrombophilia. Platelets 2006;17:528-544.
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84. Kayacioglu I, Gunay R, Saskin H, et al. The role of clopidogrel and acetylsalicylic acid in the prevention of early-phase graft occlusion due to reactive thrombocytosis after coronary artery bypass operation. Heart Surg Forum 2008;11:E152-E157.
85. Solberg Jr L.A., A. Tefferi, K.J. Oles, J.S. Tarach, R.M. Petitt, L.A. Forstrom, and M.N. Silverstein, The effects of anagrelide on human megakaryocytopoiesis. British Journal of Haematology, 1997. 99(1): p. 174-180.
86. Harrison C.N., P.J. Campbell, G. Buck, K. Wheatley, C.L. East, D. Bareford, B.S. Wilkins, J.D. van der Walt, J.T. Reilly, A.P. Grigg, P. Revell, B.E. Woodcock, and A.R. Green, Hydroxyurea Compared with Anagrelide in High-Risk Essential Thrombocythemia. New England Journal of Medicine, 2005. 353(1): p. 33-45.
87. Storen E.C. and A. Tefferi, Long-term use of anagrelide in young patients with essential thrombocythemia. Blood, 2001. 97(4): p. 863-866.
88. John Mascarenhasa,., Mark L. Heaneyb, Vesna Najfelda Proposed criteria for response assessment in patients treated in clinical trials for myeloproliferative neoplasms in blast phase (MPN-BP): Formal recommendations from the post-myeloproliferative neoplasm acute myeloid leukemia consortium. Leukemia Research Volume 36, Issue 12 , Pages 1500-1504, December 2012
89. Hans Kreipe & Kais Hussein & Gudrun Gohring & Brigitte Schlegelberger Progression of myeloproliferative neoplasms to myelofibrosis and acute leukaemia J Hematopathol (2011) 4:61-68
90. Barosi G, Mesa RA, Thiele J, Cervantes F, Campbell PJ, Verstovsek S, Dupriez B, Levine RL, Passamonti F, Gotlib J, Reilly JT, Vannucchi AM, Hanson CA, Solberg LA, Orazi A, Tefferi A; International Working Group for Myelofibrosis Research and Treatment (IWG-MRT). Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the International Working Group for Myelofibrosis Research and Treatment. Leukemia. 2008 Feb;22(2):437-8. Epub 2007 Aug 30.
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100. Cervantes F, Alvarez-Larran A, Domingo A, Arellano-Rodrigo E, Montserrat E. Efficacy and tolerability of danazol as a treatment for the anaemia of myelofibrosis with myeloid metaplasia: long-term results in 30 patients. Br J Haematol. 2005 Jun;129(6):771-5.
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Диагностика и терапия Ph-негаивных миелопролиферативных заболеваний (истинная полицитемия, эссенциальная тромбоцитопения, первичный миелофиброз)
Оглавление
СПИСОК СОКРАЩЕНИЙ
МЕТОДОЛОГИЯ РАЗРАБОТКИ КЛИНИЧЕСКИХ РЕКОМЕНДАЦИЙ.
ВВЕДЕНИЕ.
ЭТИОЛОГИЯ И ПАТОГЕНЕЗ Ph - НЕГАТИВНЫХ МПЗ.
Истинная полицитемия (МКБ X - D45).
+
Эссенциальная тромбоцитемия (МКБ X - D47.3).
Исследования при диагностике ЭТ.
Диагностические критерии ЭТ
+
Первичный миелофиброз (МКБ X - D47.1).
+
Миелопролиферативное заболевание, неклассифицируемое
+
ЗАКЛЮЧЕНИЕ
Литература.
Диагностика и терапия Ph-негаивных миелопролиферативных заболеваний (истинная полицитемия, эссенциальная тромбоцитопения, первичный миелофиброз)
Оглавление
СПИСОК СОКРАЩЕНИЙ
МЕТОДОЛОГИЯ РАЗРАБОТКИ КЛИНИЧЕСКИХ РЕКОМЕНДАЦИЙ.
ВВЕДЕНИЕ.
ЭТИОЛОГИЯ И ПАТОГЕНЕЗ Ph - НЕГАТИВНЫХ МПЗ.
Истинная полицитемия (МКБ X - D45).
+
Эссенциальная тромбоцитемия (МКБ X - D47.3).
Исследования при диагностике ЭТ.
Диагностические критерии ЭТ
+
Первичный миелофиброз (МКБ X - D47.1).
+
Миелопролиферативное заболевание, неклассифицируемое
+
ЗАКЛЮЧЕНИЕ
Литература.
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