I. Acute leukemia as malignant neoplasm is manifested by:
1. Increased rate of blast cells division.
2. Infiltrative growth.
3. Intoxication of organism.
4. The ability to metastasize.
5. Morphological abnormalities of leukemic cells.
6. Hyperalbuminemia.
7. Block of differentiation.
II. Which of the following factors may cause leukemia?
1. Smoking.
2. Aberration of the first chromosome pair.
3. Polycyclic hydrocarbons.
4. Ionizing radiation.
5. Epstein-Barr virus.
6. Ultraviolet rays.
III. The most common causes of death in leukemias are:
1. Derangements of metabolism.
2. Hemorrhage into life-important organs.
3. Sepsis.
4. Cachexia.
5. Anemia.
6. Pneumonia.
IV. Which of the following findings in the peripheral blood characterize myeloid leukemoid reaction?
1. Severe neutrophil leukocytosis with nuclear shift to the left (up to promyelocytes and myeloblasts).
2. Hiatus leukemicus.
3. The presence of the toxicity granules in myeloid cells.
4. The presence of eosinophilic-basophilic association.
5. The presence of lymphoblasts.
6. The presence of myelocytes.
7. The presence of promyelocytes.
8. Increased phagocytic activity of leukocytes.
V. Choose the most typical findings in the peripheral blood in chronic myeloid leukemia?
1. Myeloblasts, promyelocytes, myelocytes, metamyelocytes, mature neu-trophils, increased count of eosinophils and normal count of basophils.
2. Myeloblasts, promyelocytes, mature neutrophils, increased count of eosinophils and basophils.
3. Myeloblasts, metamyelocytes, mature neutrophils, normal count of eosinophils and basophils.
VI. Choose the most typical findings in the peripheral blood in acute myeloid leukemia.
1. Myeloblasts, promyelocytes, myelocytes, metamyelocytes, immature neutrophils, segmented neutrophils.